| Name | Description | SW | HW ↑ | Pub |
|---|---|---|---|---|
| Xak universe | Contains Xak series as well as spin-offs set in the same universe. | 8 | 0 | 0 |
| Xak Series | Xak is a series of medieval-themed action role-playing games by Micro Cabin. | 2 | 0 | 0 |
| Dragon Slayer universe | Games in the Dragon Slayer universe by Falcom | 13 | 0 | 0 |
| Metal Gear series | Konami's Metal Gear franchise started on the MSX. | 2 | 0 | 0 |
| Knightmare games | 4 | 0 | 0 | |
| Aleste Series | Aleste series by Compile | 3 | 0 | 0 |
| Gradius / Nemesis series | Konami's Gradius series. Known as Nemesis in Europe. | 4 | 0 | 0 |
| Compile Disc Station series | 42 | 0 | 0 | |
| Hydlide series | Hydlide series by T&E Soft | 6 | 0 | 0 |
| Lode Runner series | 4 | 0 | 0 | |
| Zanac series | 2 | 0 | 0 | |
| Laydock series | Laydock series by T&E Soft | 5 | 0 | 0 |
| Daiva series | Daiva series by T&E Soft | 3 | 0 | 1 |
| Koei Genghis Khan series | Genghis Khan series by Koei | 4 | 0 | 0 |
| Nobunaga's Ambition series | 6 | 0 | 0 | |
| Romance of the Three Kingdoms series | Romance of the Three Kingdoms series by Koei | 3 | 0 | 0 |
| Daisenryaku series | Daisenryaku series by System Soft | 6 | 0 | 0 |
| Radarsoft Topografie series | Educational topography series by Radarsoft | 3 | 0 | 0 |
| Snatcher games | Snatcher games by Konami | 2 | 0 | 0 |
| King's Valley games | King's Valley games by Konami | 6 | 0 | 0 |
| Ys series | YS is a series of RPG games by Falcom | 4 | 0 | 0 |
| Games with Game Master 2 S-RAM support | Games with support for the S-RAM in the Konami Game Master 2 cartridge. The S-RA… | 12 | 0 | 0 |
| Games with Game Master support | Games supported by the Konami Game Master cartridge | 18 | 0 | 0 |
| MSX・FAN Disk Magazine series | MSX・FAN Disk Magazines published by Tokuma Shoten | 33 | 0 | 0 |
| Dragon Disk series | Dragon Disk magazine series published by MSX-Engine | 10 | 0 | 0 |